WEC Program

Sunday, March 15, 2020
Location: Maryland Ballroom – D

4:00 pm

Opening Remarks Darryl C. Zeldin, MD, NIH/NIEHS, Research Triangle Park, NC
SESSION I: IN MEMORY OF JOHN A. OATES

Co-Chairs:

Nancy J. Brown, M.D., Vanderbilt University, Nashville, TN Lawrence Marnett, Ph.D., Vanderbilt University, Nashville, TN

4:05 pm

Drs.Brown/Marnett Tribute to Dr. Oates.

4:20 pm

Garret A. FitzGerald, MD, University of Pennsylvania, Philadelphia, PA Prostaglandins and their Inhibitors: The Legacy of John Oates.

4:45 pm

James M. Luther, MD, Vanderbilt University School of Medicine, Nashville, TN TBA.

5:10 pm

Darryl C. Zeldin, MD, NIH/NIEHS, Research Triangle Park, NC Biochemical Regulation of EET Formation and Hydrolysis: Following on the Legacy of John Oates.

5:35 pm

Coffee Break (20 min)
SESSION I: PROLM YOUNG INVESTIGATORS SESSION
(SPONSORED BY ELSEVIER/PROSTAGLANDINS AND OTHER LIPID MEDIATORS)

Co-Chairs:

To be named

5:55 pm

Speaker Introduction of Young Investigator Session

6:00 pm

Victoria Hallisey, Beth Israel Deaconess Medical Center, Boston, MA TBA

6:15 pm

Wojciech Jankiewicz, Medical College of Wisconsin, Milwaukee, WI TBA

6:30 pm

Xi Lan, Johns Hopkins School of Medicine, Baltimore, MD TBA

6:45 pm

Fumie Nakashima, Vanderbilt University Medical Center, Nashville, TN TBA

7:00 pm

Welcome Reception/Meet the Exhibitors Maryland Ballroom Foyer
MONDAY, MARCH 16, 2020

7:15-8:15 am

Trainee Roundtable: Homeland Room
ORAL PRESENTATIONS
Location: Maryland Ballroom – D
SESSION III: ROLE OF LIPID MEDIATORS IN THE RESOLUTION OF INFLAMMATION

Co-Chairs:

Dipak Panigrahy, M.D., Beth Israel Deaconess Medical Center Gabrielle Fredman, Ph.D., Albany Medical College, Albany, NY

8:30 am

Gabrielle Fredman, Ph.D., Albany Medical College, Albany, NY TBA

8:55 am

Niccolò Terrando, B.Sc. (hons), D.I.C., Ph.D., Duke University Medical Center, Durham, NC Resolution of Neuroinflammation in Postoperative Delirium.

9:20 am

John L. Wallace, Ph.D., MBA, University of Calgary & Antibe Therapeutics Inc, Toronto, Ontario, Canada Toward Safer and More Effective Analgesics: Clinical Trials of H2S-Releasing Drugs

9:45 am

Thomas E. Van Dyke, DDS, Ph.D., Forsyth Institute/Harvard Faculty of Medicine, Cambridge, MA Resolution of Oral Inflammation

10:10 am

Stephen P. Chelko, Ph.D., Johns Hopkins School of Medicine, Baltimore, MD Therapeutic Targeting of Myocardial Inflammation in Arrhythmogenic Cardiomyopathy

10:35 am

Coffee Break (20 min)
Session IV: LIPIDOMICS ANALYSIS OF OXYLIPINS IN BIOLOGICAL AND CLINICAL SAMPLES

Co-Chairs:

Nils Helge Schebb, Ph.D., University of Wuppertal, Wuppertal, Germany Co-Chair to be named

10:55 am

Edward A. Dennis, Ph.D., University of California-San Diego, CA Plasma Lipidomic Profiling in Nonalcoholic Steatohepatits (NASH)

11:20 am

John W. Newman, Ph.D., University of California, Davis, CA Pre-analytical Considerations for Bio-banked Plasma and/or Serum Lipid Mediator Investigations

11:45 am

Nicole M. Hartung, University of Wuppertal, Germany Oxylipin Analysis – Strategies to Ensure Comparable and Reproducible Results

12:00 pm

Christopher Ramsden, M.D., National Institute on Aging, Bethesda, MD Analysis of Oxylipins in Serum and Plasma following Controlled Dietary Manipulation in Patients with Chronic Headaches; Challenges and Interpretation

12:20 pm

Mathew L. Edin, Ph.D., National Institute of Environmental Health & Safety, RTP, NC Regulation of Oxylipins in Carriers of CYP2J2*7 and EPHX2 K55R Polymorphisms

12:40 pm

Lunch Break (1 hr, 20 min)
SESSION V: NOVEL INSIGHTS IN CANCER AND EICOSANOIDS

Co-Chairs:

Paola Patrignani, Ph.D., “G. d’Annunzio” University, Chieti, Italy Dieter Steinhilber, Ph.D., University of Frankfurt, Frankfurt, Germany

2:00 pm

Paola Patrignani, Ph.D., “G. d’Annunzio” University, Chieti, Italy Cancer Development and Progression and its Relation to Platelets

2:25 pm

Dieter Steinhilber, Ph.D., Goethe University Frankfurt, Frankfurt, Germany Beyond Leukotriene Formation – The Noncanonical Functions of 5-Lipoxygenase

2:50 pm

David A. Potter, M.D., Ph.D., University of Minnesota, Minneapolis, MN Novel Insights into the Role of CYP Monooxygenases in Tumor Progression

3:15 pm

Emanuela Ricciotti, Ph.D., University of Pennsylvania, Philadelphia, PA NSAID-gut Microbiota Interactions: Implications for Cancer Treatment

3:40 pm

Coffee Break (20 min)
SESSION VI: GI TRACT (COLON, LIVER, PANCREAS) AND OTHER TISSUES – INFLAMMATION/METABOLIC

Co-Chairs:

Guodong Zhang, Ph.D., University of Massachusetts, Amherst, MA Tara M. Nordgren, Ph.D., University of California, Riverside, CA

4:00 pm

Tara M. Nordgren, Ph.D., University of California, Riverside, CA Maresin-1-mediated Protection from Dust-induced Lung Inflammation is Associated with Enhanced Macrophage IL-22 Signaling

4:25 pm

Guodong Zhang, Ph.D., University of Massachusetts, Amherst, MA Soluble Epoxide Hydrolase is an Endogenous Regulator of Obesity-induced Intestinal Barrier Dysfunction and Bacterial Translocation

4:50 pm

Imad Shureiqi, M.D., University of Texas MD Anderson Cancer Center, Houston, TX PPARD, Metabolism and Chronic Inflammation of the Gastrointestinal tract: The Dark Side of a Lipid Nuclear Receptor

5:15 pm

Karsten-Henrich Weylandt, M.D., Ph.D., Brandenburg Medical School, Germany TBA

5:40 pm

End of Monday Sessions

5:45-7:15 pm

Poster Session I Location: Maryland Ballroom – ABC Meet Exhibitors – Ballroom Foyer
SESSION VI: GI TRACT (COLON, LIVER, PANCREAS) AND OTHER TISSUES – INFLAMMATION/METABOLIC

Co-Chairs:

Guodong Zhang, Ph.D., University of Massachusetts, Amherst, MA Tara M. Nordgren, Ph.D., University of California, Riverside, CA

4:00 pm

Tara M. Nordgren, Ph.D., University of California, Riverside, CA Maresin-1-mediated Protection from Dust-induced Lung Inflammation is Associated with Enhanced Macrophage IL-22 Signaling

4:25 pm

Guodong Zhang, Ph.D., University of Massachusetts, Amherst, MA Soluble Epoxide Hydrolase is an Endogenous Regulator of Obesity-induced Intestinal Barrier Dysfunction and Bacterial Translocation

4:50 pm

Imad Shureiqi, M.D., University of Texas MD Anderson Cancer Center, Houston, TX PPARD, Metabolism and Chronic Inflammation of the Gastrointestinal tract: The Dark Side of a Lipid Nuclear Receptor

5:15 pm

Karsten-Henrich Weylandt, M.D., Ph.D., Brandenburg Medical School, Germany TBA

5:40 pm

End of Monday Sessions

5:45-7:15 pm

Poster Session I Location: Maryland Ballroom – ABC Meet Exhibitors – Ballroom Foyer
TUESDAY, MARCH 17, 2020

7:15-8:15 am

Trainee Roundtable: Homeland Room
ORAL PRESENTATIONS
Location: Maryland Ballroom – D
SESSION VII: EICOSANOIDS AND HEART FAILURE

Co-Chairs:

Sachin A. Gupte, M.D., Ph.D., New York Medical College John M. Seubert, MSc, PhD, University of Alberta, Edmonton, Alberta, Canada

8:30 am

John M. Seubert, MSc, PhD, University of Alberta, Edmonton, Alberta, Canada Does Targeting Soluble Epoxide Hydrolase Preserve Cardiac and Mitochondrial Function in Aged Females?

8:55 am

Nipavan Chiamvimonvat, MD, University of California-Davis, Davis, CA Beneficial Effects of Soluble Epoxide Hydrolase Inhibitors in Heart Failure: Molecular and Cellular Mechanisms

9:20 am

Petra Rocic, Ph.D., New York Medical College, Valhalla, NY 20-HETE and Ischemic Cardiomyopathy

9:45 am

Ilaria D’agostino, “G. d’Annunzio” University, Chieti, Italy Low-dose Aspirin Protects against Elevated Blood Pressure and Cardiac Fibrosis in Mice

10:00 am

Coffee Break (20 min)
SESSION VIII: EICOSANOIDS AND THE OCULARS

Co-Chairs:

Ingrid Fleming, Ph.D., Institute for Vascular Signaling, Goethe University, Frankfurt, Germany Kip M. Connor, Ph.D., Massachusetts Eye & Ear Infirmary/Harvard, Boston, MA

10:20 am

Kip M. Connor, Ph.D., Massachusetts Eye & Ear Infirmary/Harvard, Boston, MA Therapeutic potential of bioactive lipids in neovascular AMD or Cytochrome P450 eicosanoids regulate choroidal neovascularization

10:45 am

Nicolas G. Bazan, MD, PhD, Louisiana State University Health, School of Medicine, New Orleans, LA Bioactivity and Significance of the Novel Elovanoids of Retina Function and Retinal Degenerative Diseases

11:10 am

presentation to be chosen from the abstracts TBA

11:25 pm

Ingrid Fleming, Ph.D., Goethe University, Frankfurt am Main, Germany Sola dosis facit venenum: 19,20-Dihydroxydocosapentaenoic Acid and the Retinal Vasculature

11:50 pm

Lunch Break (1 hr, 30 min)
SESSION IX: EICOSANOIDS AND THE VASCULATURE

Co-Chairs:

Victor A. Garcia, Ph.D., New York Medical College Richard Roman, Ph.D. University of Mississippi, Jackson, MS

1:20 pm

Fan Fan, M.Dl, M.S., FAHA, University of Mississippi Medical Center, Jackson, MS Role of 20-HETE in Alzheimer’s Disease-Related Dementias

1:45 pm

Anthony P. Barnes, Ph.D., Knight Cardiovascular Institute, Portland, OR Regulation of Vascular Smooth Muscle Cell Signaling by the Eicosanoid-sensing Receptor GPR39

2:10 pm

William B. Campbell, Ph.D., Medical College of Wisconsin, Milwaukee, WI TBA

2:35 pm

Victor A. Garcia, PhD, New York Medical College, Valhalla, NY Macrophage 12(S)-HETE Enhances Angiotensin II-Induced Contraction through an AT2 and BLT2 Receptor-Mediated Isothromboxane Release in Murine Aortas

3:00 pm

Coffee Break (20 min)
JOHN C. MCGIFF MEMORIAL LECTURE

3:20 pm

William B. Campbell, Ph.D., Medical College of Wisconsin, Milwaukee, WI Introduction of Awardee & Presentation

3:30 pm

Michal L. Schwartzman, Ph.D., New York Medical College TBA

4:00 pm

End of Tuesday Sessions

4:00-5:30 pm

Poster Session II
Maryland Ballroom – ABC
Meet Exhibitors – Maryland Foyer

7:30 pm

Conference Dinner and Awards Presentations Restaurant to be Names
End of Conference
17th International Winter Eicosanoid Conference – 2018
16th International Winter Eicosanoid Conference – 2016
15th International Winter Eicosanoid Conference – 2014
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